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Build AI That Makes Surgery Safer

Join a team of engineers, surgeons, and scientists developing vision systems that protect patients in the operating room and advance cell & gene therapy manufacturing.

Open Positions

Current Opportunities

We're growing our team across AI engineering, clinical operations, and product development.

AI Vision Engineer
Sterile Processing & Surgical Instrument Recognition
📍 Cambridge, UK 💼 Full-Time or Internship 🧠 Computer Vision & Deep Learning 👥 Reports to CEO

Own and improve the core vision pipeline that identifies surgical instruments being packed into trays. Work across the full ML lifecycle: data preparation, model training, evaluation, deployment, and monitoring.

Key Responsibilities

  • Improve instrument identification accuracy across diverse tray configurations and lighting conditions
  • Reduce inference latency for real-time feedback during the packing workflow
  • Build robustness against edge cases: reflective surfaces, overlapping instruments, partial occlusions, and variable wear
  • Develop and maintain the data pipeline (annotation, augmentation, model retraining)
  • Collaborate with the clinical team to translate SPD workflow requirements into technical specifications
  • Contribute to expanding platform capabilities: instrument condition assessment, tray completeness verification, and hospital inventory integration

Essential Requirements

  • Strong foundation in computer vision and deep learning (object detection, instance segmentation, image classification)
  • Hands-on experience with PyTorch or TensorFlow and modern vision architectures (YOLO, Detectron2, Vision Transformers, or similar)
  • Proficiency in Python; comfort with Git and collaborative development
  • Ability to work across the full ML lifecycle: data preparation, model training, evaluation, deployment, and monitoring
  • Genuine interest in building systems that work reliably in the real world, not just on benchmarks

Highly Valued

  • Experience with edge deployment and model optimisation (ONNX, TensorRT, quantisation)
  • Background in fine-grained visual recognition, metallic/reflective object detection, or industrial inspection
  • Familiarity with camera systems, lighting setups, and physical constraints of real-world vision deployments
  • Experience with MLOps tooling (experiment tracking, data versioning, CI/CD for ML)
  • Published research or a Master's/PhD project in a relevant area

Internship Track

  • Structured 3-month paid internship with a clear conversion path to a full-time role
  • Designed around a concrete deliverable — for example, improving instrument segmentation robustness under variable SPD lighting
  • Suited to final-year undergraduates, Master's students, or recent graduates looking for high-ownership roles
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CGT Research Scientist
iPSC & AI-Integrated Cell Manufacturing
📍 Babraham Research Campus, Cambridge, UK 💼 Full-Time or Contract 🧬 Stem Cell Biology & CGT 👥 Reports to CSO

Build a new stem cell platform from the ground up within a growing CGT company. Work at the cutting edge of AI + automation + cell therapy manufacturing, based at Babraham Research Campus.

Key Responsibilities

  • Establish and optimise iPSC culture workflows, including surface coating strategies (e.g. Matrigel, vitronectin, synthetic matrices) and scale-up approaches compatible with roller bottle and automated systems
  • Develop and evaluate organoid and 3D culture systems, including feasibility within closed or semi-automated platforms
  • Design and implement AI-assisted imaging workflows for real-time quality control of iPSC colony morphology, differentiation efficiency, and organoid formation and maturity
  • Build and curate a proprietary cell imaging dataset ("cell atlas") to support machine learning model development
  • Develop directed differentiation protocols for iPSC-derived cell types relevant to CGT and allogeneic cell therapy applications
  • Collaborate with engineering and data science teams to integrate biological workflows into the Bodhi platform
  • Contribute to grant applications, technical reports, and publications, supporting funding efforts (e.g. Innovate UK, UKRI)

Essential Requirements

  • PhD (or equivalent experience) in stem cell biology, regenerative medicine, CGT, or related field
  • Strong hands-on experience with iPSC & MSC culture and maintenance
  • Experience with stem cell QC characterisation, passaging, and differentiation workflows
  • Experience with adherent cell culture scale-up (e.g. coated surfaces, multilayer systems, microcarriers, or bioreactors)
  • Proven ability to design, execute, and troubleshoot experiments independently
  • Experience with cell imaging techniques (brightfield, phase contrast, fluorescence microscopy)
  • Strong analytical mindset and data-driven approach to experimental optimisation
  • Interest in applying AI / computational methods to biological systems

Highly Valued

  • Experience with 3D culture systems (organoids, spheroids, extracellular matrix-based systems)
  • Expertise in iPSC differentiation into therapeutically relevant lineages (e.g. neural, cardiac, hepatic, immune)
  • Familiarity with automated or semi-automated culture platforms (bioreactors, liquid handlers, robotics)
  • Experience with image-based assays and quantitative image analysis (e.g. CellProfiler, FIJI/ImageJ)
  • Programming skills (Python, R, MATLAB) for data analysis or image processing
  • Track record of peer-reviewed publications in stem cell biology, organoids, or CGT
Ask a Question

Apply for Stem Cell & CGT Research Scientist

No formal cover letter needed — tell us what excites you about this role and how your background fits.

📄
Click to upload or drag and drop
PDF, DOC, or DOCX — max 5 MB
Your information will be sent directly to the Appraiseye team. We review every application.
Why Appraiseye

What Sets Us Apart

We're building technology that matters, with a team that moves fast and cares deeply.

🔬

Real-World Impact

Your code ships to hospitals and improves patient outcomes.

🚀

Immediacy

Early-stage team, funded programs, clear direction.

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Cambridge & Philadelphia

Based in two of the strongest biotech ecosystems.